{"product_id":"glanvac-6s-zoetis","title":"Glanvac 6s Zoetis**","description":"\r\n\t\t\r\n\t\t\r\n\t\t\u003cstyle type=\"text\/css\"\u003e.csBE29F54{margin:0pt 0pt 10pt 0pt;text-align:left;text-indent:0pt} .csB2B83AB{12pt;font-weight:normal;color:#000000;font-style:normal;Arial;}\u003c\/style\u003e\r\n\t\r\n\t\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e** RECOMMEND 18g x 1\/4\" needle for vaccinating\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eB12 is made naturally by sheep and cattle, as they convert cobalt from their diet into B12 in their rumen (largest stomach). An injection containing B12 is like a “top up” if they need it…..read on!!\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eSo, What is Cobalt? \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Essential trace element required by ruminants for the synthesis of Vitamin B12\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Micro-organisms in the rumen convert dietary cobalt into Vitamin B12\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Concentration of cobalt in forages is affected by soil properties, plant species, stage of maturity, yield, pasture management and climate – seasonal variation is a huge factor in just how much cobalt is ingested.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eWhen cobalt, that is present in pasture or soil, is ingested it is converted into vitamin B12 by microbes which are active in the sheep’s rumen.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eFrom here, vitamin B12 is either utilised within the rumen or is stored in the liver.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eIf the storage capacity is full, then any excess is excreted in the urine.\u003cspan style=\"mso-spacerun:yes\"\u003e   \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eWhat are the factors influencing cobalt deficiency?\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Associated with sandy coastal soil types and higher pH soils (limestone country).\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Prolonged weathering, leaching or intensive cropping can decrease the amounts of cobalt in the soil.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eWhat does Vitamin B12 do?\u003cspan style=\"mso-spacerun:yes\"\u003e               \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eVitamin B12 is essential for the production of glucose from volatile fatty acids in the rumen.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eThe glucose translates into energy for the animal – this is required for all basic functions of life, such as cell growth, cell maturation, wool production, lactation, reproduction.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eWithout adequate levels of B12, the sheep’s body will be unable to perform basic functions that are required for it to live.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eWhat are the effects of vitamin B12 deficiency?\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Clinical signs: Loss of appetite, Decreased growth rates, Weight loss, Water ocular discharge (weeping eyes), Anaemia\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Subclinical: Reduced growth rates, Reduced wool growth, Increased tail in mob\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eThese signs can occur despite an abundance of available pasture – which explains seasonal variation, and often combines with times of high production!\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eWhat is the significance of Vitamin B12?\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• In Australia tends to be more commonly a marginal deficiency rather than severe.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Clinical signs (reduced growth rates) may not be noted but can be of significant economic importance.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• The cost of correction is small, compared to the resulting benefit. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eWho to Supplement with B12?\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eEwes:\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Ewes are the powerhouse of any sheep operation, they are highly productive with increased energy requirements\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Vaccination of ewes with Glanvac B12 one month prior to lambing increases the vitamin B12 that is stored in the foetal liver and will ensure high levels are present in the ewe’s colostrum. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Ewes supplemented pre-lamb have more energy which can help avoid pregnancy toxaemia, help produce more milk and aid in conditions like dystocia.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eLambs:\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Vitamin B12 stores in the newborn lamb’s liver have been shown to decrease rapidly in the 60 days after birth and will generally provide the lamb with adequate vitamin B12 until lamb marking. Supplementation at marking will provide the lamb with further vitamin b12 until grazing commences and cobalt can be ingested. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e• Young growing weaners are rapidly growing and are more susceptible to vitamin B12 deficiency than adult sheep regardless if the pasture is or isn’t cobalt deficient. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eIs it worth vaccinating if I am not in a deficient area? \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eAs the area around Pyramid Hill isn’t a considered a cobalt deficient area, there are sometimes questions raised as to whether it is worth using B12 vaccines. Unless you know the plasma concentration of Vitamin B12 in your sheep, it is very difficult to tell if there will be increased growth rates from using B12 – sometimes the benefit can be small enough to pay for itself, however not noticeable enough in every sheep. The increase is often only 50-100g, therefore not shown by normal weighing equipment, therefore hard to actually measure. Comments from producers over time, often talk about “lifting the tail of the mob” as these even small increases in weight combined with an increase in appetite and overall energy, often lead to less of a “tail”.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eEg;\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eLet’s pretend that three glasses are our sheep, who have varying levels of currently available B12: \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e\u003cspan style=\"mso-spacerun:yes\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eCup 1 (empty)- will benefit from a vaccination of B12 and you will see increased growth and production rates from this animal. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eCup 2- the vaccine will top this animal up and anything it doesn’t need it will excrete- mid range growth rates. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eCup 3- Only needs a little bit, will probably excrete most of it, we might not see any changes. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e\u003co:p\u003e \u003c\/o:p\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eAcross a farm there will be varying levels of “full or empty cups”. An injection of Vitamin B12 is like giving sheep Berocca- it helps top up their energy during stressful times and when the demand for energy is at its greatest, i.e, Pre-lambing, marking and weaning. \u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e\u003co:p\u003e \u003c\/o:p\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e. Cheesy Gland - bacterial infection (slow to develop), and highly contageous.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eAbscesses under the arm and at shearing time abscesses can burst.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eSheep can cough up bacteria.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e\u003co:p\u003e \u003c\/o:p\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e5 Clostridial Diseases\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e. Pulpy Kidney - change in feed, microbes in stomach not coping.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eSigns, frothing in the mouth.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e. Tetanus - scratched\/jabbed from something rusty.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e. Black Disease - infected with liver fluke\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e. Blackleg - Bruising in legs\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e. Malignant Oedema eg; rams fighting sores on head.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e\u003co:p\u003e \u003c\/o:p\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003eThese diseases kill the sheep quickly, and they decompose quickly.\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e\u003co:p\u003e \u003c\/o:p\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp class=\"csBE29F54\"\u003e\u003cspan class=\"csB2B83AB\"\u003e. Pulpy Kidney.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eChange of feed (high risk), will need to vaccinate if last dose was more than three months ago.\u003cspan style=\"mso-spacerun:yes\"\u003e  \u003c\/span\u003eIdeally wait 14 days before introducing new feed.\u003c\/span\u003e\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"250 ml","offer_id":48664742166753,"sku":"9347909002867","price":134.2,"currency_code":"AUD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0749\/2671\/9201\/files\/9347909002867_1.jpg?v=1784184911","url":"https:\/\/www.millerag.com.au\/products\/glanvac-6s-zoetis","provider":"Miller Ag Supplies","version":"1.0","type":"link"}